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Related Concept Videos

Inflammatory Bowel Disease II: Ulcerative Colitis01:20

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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
06:19

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis

Published on: May 16, 2025

The Asia-Pacific consensus on ulcerative colitis.

Choon Jin Ooi1, Kwong Ming Fock, Govind K Makharia

  • 1Department of Gastroenterology and Hepatology, Duke-NUS Graduate Medical School and Singapore General Hospital, Singapore. ooi.choon.jin@sgh.com.sg

Journal of Gastroenterology and Hepatology
|April 8, 2010
PubMed
Summary

Ulcerative colitis (UC) is rising in Asia, requiring region-specific diagnostic and management guidelines. This consensus addresses UC epidemiology and treatment, emphasizing infectious colitis exclusion and tailored care for the Asia-Pacific population.

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Last Updated: Jun 14, 2026

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
06:19

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis

Published on: May 16, 2025

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Epidemiology

Background:

  • Inflammatory Bowel Disease (IBD), specifically ulcerative colitis (UC), shows increasing prevalence in the Asia-Pacific region.
  • There is a critical need for localized diagnostic and management strategies for UC tailored to the Asia-Pacific context.
  • Current understanding and treatment protocols for UC often reflect Western data, necessitating regional adaptation.

Purpose of the Study:

  • To establish evidence-based consensus statements for the definition, epidemiology, and management of ulcerative colitis (UC) in Asia.
  • To provide clinicians with region-specific recommendations for recognizing and managing UC.
  • To address the unique challenges and considerations for UC care within the Asia-Pacific region.

Main Methods:

  • A multi-disciplinary expert group convened to develop consensus statements.
  • Literature review was conducted to gather relevant evidence on UC in Asia.
  • The Delphi method was employed for anonymous voting on consensus statements, followed by review for evidence quality and recommendation strength.

Main Results:

  • Typical UC histology and disease extent are observed in the Asia-Pacific, with increasing incidence and similar demographics to Western populations.
  • Extra-intestinal manifestations, such as primary sclerosing cholangitis, are less common than in the West.
  • Management strategies must consider factors like infectious colitis exclusion, disease severity stratification, limited biologic agent access, and hepatitis B virus screening.

Conclusions:

  • Consensus statements provide a framework for improved UC recognition and management in the Asia-Pacific.
  • Region-specific considerations, including infectious colitis, rarer extra-intestinal manifestations, and viral hepatitis screening, are crucial for effective UC care.
  • Tailored approaches to treatment, considering local practices and resource availability, are essential for optimizing outcomes in the Asia-Pacific UC population.