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Management of bleeding following major trauma: an updated European guideline
Rolf Rossaint1, Bertil Bouillon, Vladimir Cerny
1Department of Anaesthesiology, University Hospital Aachen, RWTH Aachen University, Pauwelsstrasse 30, Aachen, Germany. rrossaint@ukaachen.de
Insights
Updated guidelines offer evidence-based recommendations for managing bleeding trauma patients. These strategies focus on coagulation support, hemostatic measures, and monitoring to improve outcomes in severe injuries.
Area of Science:
- Trauma Care
- Hemorrhage Management
- Evidence-Based Medicine
Background:
- Severe trauma necessitates evidence-based guidelines for acute bleeding management to improve patient outcomes.
- Previous guidelines were established in 2007, requiring an update based on new evidence and clinical practice changes.
Purpose of the Study:
- To present an updated multidisciplinary guideline for the acute management of bleeding trauma patients.
- To incorporate new evidence and clinical practice advancements since the 2007 guideline.
Main Methods:
- Formulation of recommendations by a multidisciplinary Task Force for Advanced Bleeding Care in Trauma.
- Utilized a nominal group process and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy.
- Recommendations based on a systematic review of published literature.
Main Results:
- Introduced new recommendations for coagulation support, monitoring, and the use of local hemostatic agents, tourniquets, calcium, and desmopressin.
- Reevaluated and regraded existing recommendations based on recent literature.
- Considered changes in clinical practice, including new evidence and availability of agents/technologies.
Conclusions:
- The updated guideline provides a comprehensive, evidence-based, multidisciplinary approach.
- Aims to optimize the management of critically injured bleeding trauma patients.
Introduction:
Evidence-based recommendations are needed to guide the acute management of the bleeding trauma patient, which when implemented may improve patient outcomes.
Methods:
The multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed in 2005 with the aim of developing a guideline for the management of bleeding following severe injury. This document presents an updated version of the guideline published by the group in 2007. Recommendations were formulated using a nominal group process, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy of evidence and based on a systematic review of published literature.
Results:
Key changes encompassed in this version of the guideline include new recommendations on coagulation support and monitoring and the appropriate use of local haemostatic measures, tourniquets, calcium and desmopressin in the bleeding trauma patient. The remaining recommendations have been reevaluated and graded based on literature published since the last edition of the guideline. Consideration was also given to changes in clinical practice that have taken place during this time period as a result of both new evidence and changes in the general availability of relevant agents and technologies.
Conclusions:
This guideline provides an evidence-based multidisciplinary approach to the management of critically injured bleeding trauma patients.
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