Management of bleeding following major trauma: an updated European guideline

Rolf Rossaint1, Bertil Bouillon, Vladimir Cerny

  • 1Department of Anaesthesiology, University Hospital Aachen, RWTH Aachen University, Pauwelsstrasse 30, Aachen, Germany. rrossaint@ukaachen.de

Insights

Updated guidelines offer evidence-based recommendations for managing bleeding trauma patients. These strategies focus on coagulation support, hemostatic measures, and monitoring to improve outcomes in severe injuries.

Area of Science:

  • Trauma Care
  • Hemorrhage Management
  • Evidence-Based Medicine

Background:

  • Severe trauma necessitates evidence-based guidelines for acute bleeding management to improve patient outcomes.
  • Previous guidelines were established in 2007, requiring an update based on new evidence and clinical practice changes.

Purpose of the Study:

  • To present an updated multidisciplinary guideline for the acute management of bleeding trauma patients.
  • To incorporate new evidence and clinical practice advancements since the 2007 guideline.

Main Methods:

  • Formulation of recommendations by a multidisciplinary Task Force for Advanced Bleeding Care in Trauma.
  • Utilized a nominal group process and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy.
  • Recommendations based on a systematic review of published literature.

Main Results:

  • Introduced new recommendations for coagulation support, monitoring, and the use of local hemostatic agents, tourniquets, calcium, and desmopressin.
  • Reevaluated and regraded existing recommendations based on recent literature.
  • Considered changes in clinical practice, including new evidence and availability of agents/technologies.

Conclusions:

  • The updated guideline provides a comprehensive, evidence-based, multidisciplinary approach.
  • Aims to optimize the management of critically injured bleeding trauma patients.
Abstract

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