A selective electrochemical method of glycosylation of 3beta-hydroxy-Delta 5-steroids
Jacek W Morzycki1, Zenon Łotowski, Leszek Siergiejczyk
1Institute of Chemistry, University of Białystok, Piłsudskiego 11/4, 15-443 Białystok, Poland. morzycki@uwb.edu.pl
Carbohydrate Research
|April 8, 2010
Abstract:
A new electrochemical glycosylation method is presented. According to the method cholesterol and other 3beta-hydroxy-Delta(5)-steroids can be selectively transformed to glycosides using non-activated sugars. The method is also useful for the synthesis of glycoconjugates with sugar linked to a steroid moiety by an ether bond.
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