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Updated: Jun 14, 2026

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
Liver transplantation in children: update 2010
Binita M Kamath1, Kim M Olthoff
1Department of Pediatrics, University of Toronto, Toronto, ON M5S 1A1, Canada. binita.kamath@sickkids.ca
Insights
Pediatric liver transplant recipients face new challenges including long-term medication effects and organ shortages. Addressing these requires a multidisciplinary team approach for improved patient outcomes.
Area of Science:
- Pediatric Hepatology
- Transplant Surgery
- Immunosuppression Therapy
Background:
- Improving survival rates in pediatric liver transplantation present new challenges.
- Long-term complications of immunosuppressive therapy are a growing concern.
- Organ shortages impact waiting list morbidity and mortality.
Purpose of the Study:
- To highlight the evolving needs of pediatric liver transplant recipients.
- To emphasize the importance of managing long-term post-transplant issues.
- To underscore the necessity of collaborative care models.
Main Methods:
- This study is a review of current challenges in pediatric liver transplantation.
- It synthesizes information on post-transplant complications and quality of life.
- It discusses the role of various healthcare professionals.
Main Results:
- Key concerns include immunosuppression side effects and withdrawal.
- Quality of life for transplant recipients is a significant consideration.
- The persistent shortage of donor organs remains a critical issue.
Conclusions:
- Effective management of pediatric liver transplant recipients demands a comprehensive, multidisciplinary approach.
- Collaboration among pediatricians, transplant specialists, and support services is crucial.
- Addressing long-term complications and organ availability is vital for improving patient outcomes.
Abstract:
Pediatric liver transplant recipients represent an important target population for primary care health professionals as well as transplant practitioners. With improving patient and graft survival, new concerns now face health care professionals caring for the transplant community, namely the long-term complications of immunosuppressive therapy and the potential for withdrawal of immunosuppression, transplant recipients' quality of life, and the persistent shortage of donor organs leading to morbidity and mortality on the waiting list. These issues require constant collaboration between pediatricians, transplant hepatologists, transplant surgeons, nurses, dieticians, social workers, psychologists, and other supporting services.
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