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Updated: Jun 14, 2026

Induction and Validation of Cellular Senescence in Primary Human Cells
Published on: June 20, 2018
Senescence and death of plant organs: nutrient recycling and developmental regulation
Anne Guiboileau1, Rodnay Sormani, Christian Meyer
1Institut Jean-Pierre-Bourgin (IJPB), UMR 1318, bâtiment 2, Institut National de la Recherche Agronomique, route de Saint-Cyr, Versailles cedex, France.
Abstract:
Senescence and programmed cell death are important features for plant development. By allowing nutrient recycling and reallocation all along plant life, senescence contributes to the plant survival and the developmental program. This review first presents the concept of senescence in the global whole-plant life story, with an emphasis on the control exerted by flowering. It then focuses on leaf-senescence and its control by hormones, nutrients and development. The role of autophagy and of the Target of Rapamycin (TOR) kinase as potential regulators integrating environmental and endogenous signals, which control cell proliferation, reprogramming and nutrient management, is finally considered.
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