Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Radiological Approach to Severe Respiratory Infections and Pulmonary Complications in Immunocompromised Patients.

Seminars in respiratory and critical care medicine·2026
Same author

Reply: From the authors of the ERS/ATS statement on the international multidisciplinary classification of the interstitial pneumonias.

The European respiratory journal·2026
Same author

Analysis of SCLC subtype markers (ASCL1, NEUROD1, POU2F3, YAP1), DLL3, OTP, and TTF1 in 300 lung carcinoids and enteropancreatic neuroendocrine tumours.

Histopathology·2026
Same author

A Prospective Study of Safety and the Incremental Diagnostic Value of Transbronchial Cryobiopsy Incorporated into Robotic-Assisted Bronchoscopy in a Cancer Population.

Lung·2025
Same author

Microbiome analysis of 940 lung cancers in never-smokers reveals lack of clinically relevant associations.

Nature communications·2025
Same author

Uncovering the role of LINE-1 in the evolution of lung adenocarcinoma.

Nature·2025
Same journal

Wearable-derived activity and physiological changes following pleural intervention in malignant pleural effusion.

Chest·2026
Same journal

The effect of a two-day stay at high altitude (2500 m) on right ventricular afterload and oxygen delivery in patients with pulmonary vascular disease A randomized controlled crossover trial.

Chest·2026
Same journal

A Comparative Study of Radiation Exposure in Conventional and Robotic Bronchoscopy.

Chest·2026
Same journal

Independent Prognostic Contributions of Anti-Ro52 and Anti-MDA5 in Autoimmune-Associated Interstitial Lung Disease.

Chest·2026
Same journal

Lung aeration and gas exchange in SGA or AGA infants with moderate-severe BPD: secondary analysis of the PATH-BPD study.

Chest·2026
Same journal

Lung Cancer Incidence and Mortality after Negative Low-Dose CT Screening Results.

Chest·2026
See all related articles

Related Experiment Videos

Bronchiolar disorders: a clinical-radiological diagnostic algorithm.

Arun Devakonda1, Suhail Raoof, Arthur Sung

  • 1Division of Pulmonary and Critical Care Medicine, New York Methodist Hospital, 506 Sixth St, Brooklyn, NY 11215, USA.

Chest
|April 8, 2010
PubMed
Summary
This summary is machine-generated.

Diagnosing bronchiolar disorders is challenging due to nonspecific symptoms. High-resolution computed tomography (HRCT) scanning offers characteristic patterns to differentiate conditions like respiratory bronchiolitis and constrictive bronchiolitis.

Related Experiment Videos

Area of Science:

  • Pulmonary Medicine
  • Radiology
  • Diagnostic Imaging

Background:

  • Bronchiolar disorders present with nonspecific respiratory symptoms, complicating diagnosis.
  • Clinical history and initial tests like chest X-rays and pulmonary function tests often lack specificity.
  • Small airways involvement may be suggested by wheezing and air trapping.

Purpose of the Study:

  • To provide a practical diagnostic algorithm for bronchiolar disorders.
  • To highlight the utility of high-resolution CT (HRCT) scanning in diagnosing these conditions.
  • To describe characteristic HRCT patterns associated with different bronchiolar disorders.

Main Methods:

  • Review of clinical presentations and diagnostic challenges in bronchiolar disorders.
  • Emphasis on the role of high-resolution CT (HRCT) scanning in differential diagnosis.
  • Description of three key HRCT patterns: tree-in-bud, ill-defined centrilobular ground-glass nodules, and mosaic attenuation.

Main Results:

  • HRCT scanning is a crucial tool for diagnosing difficult bronchiolar disorder cases.
  • Distinct HRCT patterns aid in differentiating subtypes: tree-in-bud (infections), ground-glass nodules (respiratory bronchiolitis, hypersensitivity pneumonitis), and mosaic attenuation (air-trapping, constrictive bronchiolitis).

Conclusions:

  • HRCT scanning provides characteristic findings essential for diagnosing bronchiolar disorders.
  • An algorithmic approach utilizing HRCT patterns can guide clinicians in differentiating these challenging conditions.
  • Recognizing specific HRCT patterns improves diagnostic accuracy for small airways diseases.