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Updated: Jun 14, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

Sequence-selective targeting of duplex DNA by peptide nucleic acids

Peter E Nielsen1

  • 1University of Copenhagen, The Panum Institute, Department of Cellular and Molecular Medicine, Blegdamsvej 3c, DK-2200, Copenhagen, Denmark. ptrn@sund.ku.dk

Current Opinion in Molecular Therapeutics
|April 8, 2010
PubMed
Summary

Peptide nucleic acid (PNA) offers precise gene targeting for genetic therapies and gene repair. Novel PNA modifications enhance DNA recognition, enabling new therapeutic strategies.

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