Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mass Spectrometry: Alcohol Fragmentation

Mass Spectrometry: Alcohol Fragmentation

Alcohols (R-OH) ionize to lose one non-bonded electron from the oxygen atom, forming molecular ions. Due to their tendency to fragment rapidly, the intensity of the molecular ion peak in the mass spectrum is weak or sometimes absent. The fragmentation patterns for alcohols occur in two ways, i.e. ⍺-cleavage and dehydration. During ⍺-cleavage, the bond at the ⍺-position adjacent to the hydroxyl group cleaves to give a resonance-stabilized cation and a radical. However, intramolecular dehydration...

Production of Alcohol

Production of Alcohol

Continuous fermentation is a key strategy in industrial ethanol production, particularly when efficiency, scalability, and high yields are essential. This approach allows for uninterrupted operation and optimized resource utilization. The primary feedstock, corn starch, undergoes enzymatic hydrolysis facilitated by α-amylase and glucoamylase. These enzymes break down the starch into fermentable sugars such as glucose, which are readily assimilated by fermentative microorganisms.Fermentation...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Patient-specific modeling identifies metabolic interventions for reversing glucose use reprogramming in alcohol-associated hepatitis.

Communications biology·2026

Same author

The role of choline in neurodevelopment.

Pediatric research·2026

Same author

The art (and necessity) of saying no: advice to early career investigators.

Pediatric research·2026

Same author

Beyond disclosure: setting standards for AI use in publishing in the journal Pediatric Research.

Pediatric research·2026

Same author

Systematic review of terminology, definitions, and eligibility criteria in trials of neonatal encephalopathy, hypoxic-ischemic encephalopathy, and perinatal asphyxia.

Pediatric research·2026

Same author

Choline attenuates bilirubin induced effects on tyrosine phosphorylation and distribution in lipid rafts of L1 cell adhesion molecule in vivo.

Pediatric research·2026

Same journal

COVID-19 pandemic-related changes in utilization of telehealth and treatment overall for alcohol use problems.

Alcoholism, clinical and experimental research·2022

Same journal

The relationship between fathers' heavy episodic drinking and fathering involvement in five Asia-Pacific countries: An individual participant data meta-analysis.

Alcoholism, clinical and experimental research·2022

Same journal

Screening for hazardous alcohol use in the Emergency Department: Comparison of phosphatidylethanol with the Alcohol Use Disorders Identification Test and the Timeline Follow-back.

Alcoholism, clinical and experimental research·2022

Same journal

Combination treatment with varenicline and naltrexone reduces World Health Organization risk drinking levels.

Alcoholism, clinical and experimental research·2022

Same journal

College students' virtual and in-person drinking contexts during the COVID-19 pandemic.

Alcoholism, clinical and experimental research·2022

Same journal

Does state repeal of alcohol exclusion laws increase problem drinking?

Alcoholism, clinical and experimental research·2022

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 14, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

Advancing alcohol biomarkers research.

Cynthia F Bearer¹, Shannon M Bailey, Jan B Hoek

¹Division of Neonatology, Department of Pediatrics, University of Maryland Hospital for Children, Baltimore, Maryland, USA.

Alcoholism, Clinical and Experimental Research

|April 9, 2010

Summary

This summary is machine-generated.

Developing reliable biomarkers for alcohol use and related diseases is crucial for research and clinical applications. This workshop summarized progress and recommended strategies to advance alcohol biomarker discovery and implementation.

More Related Videos

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Published on: January 7, 2019

Related Experiment Videos

Last Updated: Jun 14, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Published on: January 7, 2019

Area of Science:

Biomarker research
Alcohol use disorders
Medical diagnostics

Background:

Biomarkers for detecting alcohol consumption and related diseases are vital for research and clinical practice.
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) convened a workshop in 2008 to discuss progress in alcohol biomarker development.

Purpose of the Study:

To review recent advancements in the development and application of biomarkers for alcohol use and alcohol-induced disorders.
To formulate recommendations for stimulating and advancing research in alcoholism biomarkers.

Main Methods:

Summarized the history and goals of alcohol biomarker research.
Reviewed the current status of established and novel alcohol biomarkers, including validation studies.
Incorporated perspectives on regulatory issues from various institutions and industries.

Main Results:

Discussions covered strategies for biomarker discovery and application.
The relevance of animal studies and basic science in biomarker development was addressed.
Opportunities for clinical and commercial applications of alcohol biomarkers were explored.

Conclusions:

The article highlights key perspectives and topics that formed the basis for recommendations.
Enhancing alcohol biomarker research requires strategic advancements in discovery, validation, and application.