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The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival

Stephanie R Shames1, Wanyin Deng, Julian A Guttman

  • 1Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.

Cellular Microbiology
|April 9, 2010
PubMed
Summary

Enteropathogenic Escherichia coli (EPEC) uses the effector EspZ to protect host cells from damage. EspZ interacts with host CD98, promoting cell survival mechanisms involving focal adhesion kinase (FAK).

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