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Related Concept Videos

Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
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Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
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Chronic Pancreatitis I: Introduction01:24

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Rheumatic Heart Disease I: Introduction01:23

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Iris Fixation via External Pentagram Suturing
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Chronic periaortitis with antiphospholipid syndrome.

Hyoun-Ah Kim1, Je-Hwan Won, Chang-Hee Suh

  • 1Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea.

International Journal of Rheumatic Diseases
|April 9, 2010
PubMed
Summary

Chronic periaortitis (CP) is a rare fibroinflammatory condition. This study reports the first known case linking CP with antiphospholipid syndrome, suggesting a potential autoimmune connection.

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Area of Science:

  • Rheumatology
  • Vascular Inflammation
  • Autoimmune Diseases

Background:

  • Chronic periaortitis (CP) is a rare retroperitoneal fibroinflammatory condition.
  • CP often leads to obstruction of adjacent structures.
  • Previous associations include Hashimoto's thyroiditis, SLE, and Sjögren's syndrome.

Observation:

  • This study details the first reported case of antiphospholipid syndrome (APS) in a patient diagnosed with CP.
  • The patient presented with clinical manifestations suggestive of both conditions.

Findings:

  • The co-occurrence of CP and APS suggests a potential shared autoimmune etiology.
  • This case expands the known spectrum of autoimmune conditions associated with chronic periaortitis.

Implications:

  • Further research into the autoimmune mechanisms underlying CP is warranted.
  • This finding may impact diagnostic approaches and treatment strategies for patients with CP.
  • Understanding the link between CP and APS could improve patient outcomes.