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Updated: Jun 14, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Acute retrobulbar optic neuritis and macular detachment associated with morning glory optic disc anomaly
Marjorie A Murphy1, Robert H Janigian, Theodoros Filippopoulos
1Department of Ophthalmology, APC 7, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA. margiemurphy@cox.net
Abstract:
A 31-year-old woman with morning glory optic disc anomaly (MGDA) developed acute retrobulbar optic neuritis and a bullous macular detachment. MRI demonstrated truncation of the perineural space of the affected optic nerve as well as focal optic nerve enhancement. Optical coherence tomography (OCT) showed retinoschisis associated with the macular detachment. The MRI and OCT findings support the vitreous as the source of the subretinal fluid. This is the first reported case of optic neuritis in MGDA.
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