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Related Concept Videos

Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
The Nativist Approach01:21

The Nativist Approach

The nativist approach to infant cognitive development proposes that infants are born with inherent knowledge structures that allow them to interpret the world almost immediately. This perspective contrasts with earlier developmental theories, such as those proposed by Jean Piaget, which emphasized a more gradual acquisition of cognitive abilities through interaction with the environment. One key concept in this approach is object permanence — the understanding that objects continue to exist...
Heritability01:06

Heritability

Heritability is a statistical concept that measures the degree to which genetic differences among individuals contribute to trait variations within a population. It is a fundamental idea in genetics, often prone to misinterpretation. Heritability is expressed as a percentage, reflecting the proportion of variation in a specific trait across a population that can be linked to genetic differences. However, it's important to understand that heritability does not determine how "genetic" a trait is,...
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...

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Related Experiment Video

Updated: Jun 14, 2026

Generating a Reproducible Model of Mid-Gestational Maternal Immune Activation using Poly(I:C) to Study Susceptibility and Resilience in Offspring
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A genetic perspective on infant mortality.

Tahnee N Causey1, Joann N Bodurtha, Nancy Ford

  • 1Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23298-0033, USA. tcausey@mcvh-vcu.edu

Southern Medical Journal
|April 9, 2010
PubMed
Summary
This summary is machine-generated.

Infant mortality (IM) has complex genetic and environmental causes. This study identifies genetic factors contributing to IM in Virginia, offering insights for clinical risk assessment and prevention strategies.

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Area of Science:

  • Genetics and Genomics
  • Public Health
  • Neonatal Medicine

Background:

  • Infant mortality (IM) persists as a major public health challenge despite medical advancements.
  • IM arises from intricate interactions between genetic and environmental factors.
  • Virginia's leading causes of IM include prematurity, low birth weight, congenital anomalies, and sudden infant death syndrome (SIDS).

Purpose of the Study:

  • To investigate the genetic contributions to infant mortality (IM) using data from Virginia.
  • To discuss the role of single gene disorders and genetic polymorphisms in IM.
  • To equip clinicians with information for identifying high-risk pregnancies and guiding preventative health messages.

Main Methods:

  • Analysis of infant mortality data from Virginia.
  • Review of genetic factors, including single gene disorders and polymorphisms.
  • Exploration of clinical implications for risk identification and intervention.

Main Results:

  • Genetic factors play a significant role in various causes of infant mortality.
  • Specific genetic contributions to disorders of prematurity, congenital anomalies, and SIDS are highlighted.
  • Identification of women at higher risk for adverse perinatal outcomes is crucial.

Conclusions:

  • Understanding genetic contributions is vital for addressing infant mortality.
  • While preconceptional genetic prevention is limited, risk assessment and targeted interventions are key.
  • Simple health messages can empower women of child-bearing age to reduce IM risks.