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Updated: Jun 14, 2026

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
Published on: August 28, 2015
Physicochemical Characterization, in vitro Release and Permeation Studies of Respirable Rifampicin-Cyclodextrin
1Department of Pharmaceutics, B. L. D. E. A's College of Pharmacy, BLDE University Campus, Bijapur -586 103, India.
Abstract:
The inclusion complexes of rifampicin with sucralose and beta-cyclodextrins were prepared by spray drying method. The complexes were characterized by size analyses, scanning electron microscopy, differential scanning calorimetry and x-ray diffraction methods. The results indicated the amorphous nature of resultant products. The solubility, in vitro release and skin permeation of the drug were enhanced after formation of inclusion complexes. The in vitro release and permeation of the inclusion complexes were greater in simulated lung fluid as compared to pure drug.
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