Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 14, 2026

Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy

Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy

Published on: July 15, 2021

TiArA: a virtual appliance for the analysis of Tiling Array data.

Jason A Greenbaum¹, Erika Assarsson, Jo L Chung

¹Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America. jgbaum@liai.org

|April 9, 2010

Summary

Genomic tiling array analysis is simplified with Tiling Array Analyzer (TiArA). This software offers a user-friendly interface for processing Affymetrix tiling array data, improving accessibility for researchers.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

HLA tapasin independence: broader peptide repertoire and HIV control.

Proceedings of the National Academy of Sciences of the United States of America·2020

Same author

Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4<sup>+</sup> T Cells in COVID-19.

Cell·2020

Same author

Comparison of HLA ligand elution data and binding predictions reveals varying prediction performance for the multiple motifs recognized by HLA-DQ2.5.

Immunology·2020

Same author

Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction.

Cell·2020

Same author

Interferon-γ Release Assay for Accurate Detection of Severe Acute Respiratory Syndrome Coronavirus 2 T-Cell Response.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2020

Same author

Cross-reactive memory T cells and herd immunity to SARS-CoV-2.

Nature reviews. Immunology·2020

Area of Science:

Bioinformatics
Genomics
Computational Biology

Background:

Genomic tiling arrays have been utilized since 2003.
A lack of user-friendly analysis tools hinders their widespread adoption.

Purpose of the Study:

To introduce Tiling Array Analyzer (TiArA), a software solution for genomic tiling array data analysis.
To provide a graphical interface for essential data processing steps.

Main Methods:

TiArA offers background subtraction and normalization using empirical measurements from nonspecific probes.
Data summarization is included for processed Affymetrix tiling array data.

Main Results:

TiArA provides a user-friendly graphical interface for tiling array data analysis.

More Related Videos

Rapid Setup of Tissue Microarray and Tiled Area Imaging on the Multiplexed Ion Beam Imaging Microscope Using the Tile/SED/Array Interface

Rapid Setup of Tissue Microarray and Tiled Area Imaging on the Multiplexed Ion Beam Imaging Microscope Using the Tile/SED/Array Interface

Published on: September 15, 2023

Related Experiment Videos

Last Updated: Jun 14, 2026

Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy

Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy

Published on: July 15, 2021

Rapid Setup of Tissue Microarray and Tiled Area Imaging on the Multiplexed Ion Beam Imaging Microscope Using the Tile/SED/Array Interface

Rapid Setup of Tissue Microarray and Tiled Area Imaging on the Multiplexed Ion Beam Imaging Microscope Using the Tile/SED/Array Interface

Published on: September 15, 2023

The software implements background signal measurement and normalization for consistent data processing.

Conclusions:

TiArA is available as a standalone Linux program and a cross-platform virtual machine.
The software can be accessed as a Debian package or virtual appliance.