Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Influenza01:27

Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
Coronavirus01:29

Coronavirus

Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lineage-specific chromatin poising enforced by ETS-IRF composite elements determines the divergent interferon responses of plasmacytoid dendritic cells and epithelial cells.

bioRxiv : the preprint server for biology·2026
Same author

Profiling RNA metabolism to understand tissue and subcellular clearance of therapeutic RNA.

Drug metabolism and disposition: the biological fate of chemicals·2026
Same author

A scoping review of Dialectical Behavior Therapy with patients with minoritized identity constructs.

Counselling and psychotherapy research·2025
Same author

The use of cost analysis in examinations of health coaching interventions: a scoping review protocol.

BMJ open·2025
Same author

Mechanisms of AAV neutralization by human alpha-defensins.

PLoS pathogens·2025
Same author

Corrigendum to 'A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption' [The Journal of Pharmacology and Experimental Therapeutics 392 (2025) 103597].

The Journal of pharmacology and experimental therapeutics·2025
Same journal

Correction to: Resolution of Skeletal Muscle Inflammation: Role of Specialized Pro-resolving Lipid Mediators in the Recovery from Exercise, Injury, and Disease.

Current topics in microbiology and immunology·2026
Same journal

Resolution Biology in Soft Tissue Joint Disease.

Current topics in microbiology and immunology·2026
Same journal

A 25+ Year Journey on Yeast-Regulated Cell Death Research.

Current topics in microbiology and immunology·2026
Same journal

Adoptive T-Cell Immunotherapy.

Current topics in microbiology and immunology·2026
Same journal

Resolution Pharmacology Targeting the Melanocortin System.

Current topics in microbiology and immunology·2026
Same journal

Resolution of Skeletal Muscle Inflammation: Role of Specialized Pro-resolving Lipid Mediators in the Recovery from Exercise, Injury, and Disease.

Current topics in microbiology and immunology·2026
See all related articles

Related Experiment Video

Updated: Jun 14, 2026

An Efficient Method for Adenovirus Production
10:06

An Efficient Method for Adenovirus Production

Published on: June 10, 2021

Adenovirus.

Jason G Smith1, Christopher M Wiethoff, Phoebe L Stewart

  • 1Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA, 92037, USA.

Current Topics in Microbiology and Immunology
|April 9, 2010
PubMed
Summary
This summary is machine-generated.

Human adenoviruses (HAdV) cause various infections and are used in gene therapy. Further research into HAdV structure and host interactions is vital for understanding disease and improving vector applications.

More Related Videos

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
11:48

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

Related Experiment Videos

Last Updated: Jun 14, 2026

An Efficient Method for Adenovirus Production
10:06

An Efficient Method for Adenovirus Production

Published on: June 10, 2021

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
11:48

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

Area of Science:

  • Virology
  • Molecular Biology
  • Immunology

Background:

  • Human adenoviruses (HAdV) encompass 53 serotypes across species A-G.
  • Numerous HAdV serotypes are linked to acute respiratory, gastrointestinal, and ocular infections.
  • Replication-defective HAdV-5 vectors are utilized in gene transfer and vaccine delivery.

Purpose of the Study:

  • To highlight the importance of understanding Adenovirus (AdV) biology.
  • To emphasize the need for improved knowledge of AdV structure and host interactions.
  • To underscore the significance of these insights for AdV pathogenesis and vector development.

Main Methods:

  • Review of existing literature on Adenovirus (AdV) biology.
  • Analysis of AdV structure and host interaction mechanisms.
  • Discussion of current research efforts and future directions.

Main Results:

  • Significant progress has been made in understanding AdV biology.
  • Knowledge gaps persist regarding AdV structure and host interactions.
  • Ongoing research aims to elucidate AdV pathogenesis and optimize vector applications.

Conclusions:

  • A comprehensive understanding of AdV structure and host interactions is incomplete.
  • Further research is crucial for deciphering AdV pathogenesis.
  • Enhanced knowledge will enable the optimal use of AdV vectors in biomedical applications.