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Chronic stress causes amygdala hyperexcitability in rodents

J Amiel Rosenkranz1, Emily R Venheim, Mallika Padival

  • 1Department of Cellular and Molecular Pharmacology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA. jeremy.rosenkranz@rosalindfranklin.edu

Biological Psychiatry
|April 10, 2010
PubMed
Summary

Chronic stress increases amygdala neuron excitability by reducing regulatory influences, potentially explaining hyperresponsiveness in conditions like PTSD and facilitating anxiety or depression.

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