Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cocaine: a risk factor for necrotizing enterocolitis.

R Porat1, N Brodsky

  • 1Temple University School of Medicine, Department of Pediatrics, Albert Einstein Medical Center, Philadelphia, PA 19141.

Journal of Perinatology : Official Journal of the California Perinatal Association
|March 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Overexpression of the CBF2 transcriptional activator in Arabidopsis suppresses the responsiveness of leaf tissue to the stress hormone ethylene.

Plant biology (Stuttgart, Germany)·2010
Same author

Induction of Resistance to Penicillium digitatum in Grapefruit by the Yeast Biocontrol Agent Candida oleophila.

Phytopathology·2008
Same author

Effect of pulsed short-wave diathermy on pain and function of subjects with osteoarthritis of the knee: a placebo-controlled double-blind clinical trial.

Clinical rehabilitation·2005
Same author

Effect of antioxidants on apoptosis and cytokine release in fetal rat Type II pneumocytes exposed to hyperoxia and nitric oxide.

Cytokine·2004
Same author

Gene transfer by viral vectors into blood vessels in a rat model of retinopathy of prematurity.

The British journal of ophthalmology·2001
Same author

A prospective randomized, controlled trial comparing synchronized nasal intermittent positive pressure ventilation versus nasal continuous positive airway pressure as modes of extubation.

Pediatrics·2001

Maternal cocaine use may lead to necrotizing enterocolitis (NEC) in full-term infants, even without typical risk factors. This condition requires a high index of suspicion for prompt diagnosis and treatment.

Area of Science:

  • Neonatal Medicine
  • Pediatric Gastroenterology
  • Toxicology

Background:

  • Necrotizing enterocolitis (NEC) predominantly affects preterm infants with low birth weight.
  • NEC can also occur in mature infants, often linked to compromised gastrointestinal blood flow.
  • This study investigates NEC in larger infants without typical risk factors.

Purpose of the Study:

  • To report on four cases of necrotizing enterocolitis in term/near-term infants.
  • To highlight the association between maternal cocaine use and NEC in this population.
  • To emphasize the importance of considering NEC in infants with in utero cocaine exposure.

Main Methods:

  • Case series of four infants with necrotizing enterocolitis.
  • Review of clinical presentation, including abdominal distention, bloody stools, vomiting, and residuals.

Related Experiment Videos

  • Correlation with maternal history of cocaine use.

    • Main Results:

    • All four infants had a history of maternal cocaine use and presented with NEC symptoms.
    • One infant experienced severe deterioration and died; the other three survived with medical management.
    • No other known risk factors for NEC were identified in these cases.

    Conclusions:

    • Maternal cocaine use is a potential risk factor for necrotizing enterocolitis in term and near-term infants.
    • A high index of suspicion for NEC and feeding intolerance is crucial in exposed infants.
    • Early recognition and management are vital for improving outcomes in affected neonates.