Cardiovascular risk stratification in unselected primary care patients with newly detected arterial hypertension

Thomas Dieterle1, Joerg-Peter Sigle, Gunar Bengel

  • 1Medical Outpatient Department, University Hospital Basel, Basel, Switzerland. dieterlet@uhbs.ch

Insights

Newly detected arterial hypertension patients often have high cardiovascular risk. Many exhibit multiple risk factors and target organ damage, necessitating early intervention for better outcomes.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Preventive Medicine

Background:

  • Cardiovascular risk (CVR) stratification is crucial for managing arterial hypertension.
  • Limited data exist on CVR factors (CVRFs), target organ damage (TOD), and overall CVR in newly diagnosed hypertensive outpatients.

Purpose of the Study:

  • To assess CVRFs, TOD, and overall CVR in general medical outpatients with newly detected arterial hypertension.
  • To analyze the prevalence of these factors using comprehensive diagnostic methods.

Main Methods:

  • Screened 2615 outpatients for elevated office blood pressure (OBP).
  • Analyzed data from 212 patients with newly detected hypertension, including OBP, ambulatory blood pressure (ABP) monitoring, fundoscopy, urinalysis, ECG, and echocardiography.
  • Calculated CVR using WHO/ISH guidelines.

Main Results:

  • 76.9% of patients had sustained hypertension based on ABP monitoring.
  • 61.3% had 1-2 CVRFs, and 33.0% had ≥3 CVRFs.
  • 26.4% showed TOD, 5.6% had diabetes, and 7.1% had associated clinical conditions (ACCs).
  • 71.7% of patients were classified as high CVR risk.

Conclusions:

  • Newly detected arterial hypertension in general medical outpatients is frequently associated with multiple CVRFs, TOD, and ACCs.
  • The majority of these patients present with high overall cardiovascular risk, underscoring the need for early and comprehensive management.
  • No significant differences in CVRFs, TOD, or ACCs were observed between white coat and sustained hypertensives.

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