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The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
A multilevel analysis of tuberculosis associated factors
Maria Jacirema Ferreira Gonçalves1, Antonio Carlos Ponce de Leon, Maria Lúcia Fernandes Penna
1Escola de Enfermagem de Manaus, Universidade Federal do Amazonas, Brasil. jaciremagoncalves@ufam.edu.br
Revista De Salud Publica (Bogota, Colombia)
|April 10, 2010
Summary
Acquired immunodeficiency syndrome (AIDS) significantly increases tuberculosis (TB) incidence in Brazil, particularly in low-income areas. Metropolitan regions showed varied TB distribution, influenced by AIDS and income interactions.
Area of Science:
- Epidemiology
- Public Health
- Infectious Disease Dynamics
Background:
- Tuberculosis (TB) remains a significant public health challenge globally.
- Understanding the interplay between TB and other infectious diseases like Acquired Immunodeficiency Syndrome (AIDS) is crucial for effective control strategies.
- Previous research in Brazil has not fully elucidated the impact of AIDS on TB incidence rates.
Purpose of the Study:
- To evaluate the association between TB and AIDS in Brazilian metropolitan regions.
- To estimate the determinant effects and factors influencing TB incidence rates.
- To analyze the period from 2001 to 2003 for these associations.
Main Methods:
- A Poisson longitudinal multilevel model was employed.
- Data included annual TB case numbers by municipality and year, with population as an offset.
- Independent variables comprised AIDS incidence, low-income household percentage, demographic density, and TB cure rate, analyzed by municipality and Brazilian geographic area.
Main Results:
- Low income, demographic density, AIDS incidence, and Brazilian geographic area were significantly associated with tuberculosis incidence (p<0.05).
- The TB cure rate did not show a significant association with TB incidence.
- A significant interaction between AIDS and low income was observed, modifying the effect of AIDS on TB incidence.
Conclusions:
- Acquired immunodeficiency syndrome (AIDS) has emerged as a significant morbidity factor for tuberculosis in Brazil.
- The interaction between income and AIDS, alongside the substantial contribution of metropolitan regions, influenced tuberculosis distribution heterogeneously across large Brazilian areas.
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