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Related Experiment Video

Updated: Jun 14, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

Published on: July 28, 2020

Abdominal soft tissue sarcoma: a multicenter retrospective study.

Junichi Nishimura1, Eiichi Morii, Tsuyoshi Takahashi

  • 1Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan. jnishimura@orh.go.jp

International Journal of Clinical Oncology
|April 10, 2010
PubMed
Summary
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This study analyzed retroperitoneal and abdominal soft tissue sarcomas (STS) in Japan, finding liposarcomas larger but with better recurrence-free survival than leiomyosarcomas. Low-grade STS showed significantly better overall survival.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Clinical Epidemiology

Background:

  • Soft tissue sarcomas (STS) are rare mesenchymal tumors with diverse subtypes.
  • Limited data exists on the clinical characteristics and prognosis of STS in Japan.
  • This study addresses the need for data on Japanese patients with retroperitoneal and abdominal STS.

Purpose of the Study:

  • To clarify the clinical features of retroperitoneal and abdominal STS in Japanese patients.
  • To determine the prognostic profiles and outcomes for these patients.
  • To compare clinical characteristics and survival between leiomyosarcoma and liposarcoma subtypes.

Main Methods:

  • Retrospective analysis of 82 patients who underwent surgery for retroperitoneal and abdominal STS (2000-2007).

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Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

Related Experiment Videos

Last Updated: Jun 14, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing (Neo)adjuvant Therapies

Published on: July 28, 2020

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

  • Inclusion of patient demographics, clinical features, histological subtypes, and surgical outcomes.
  • Statistical analysis of overall survival, recurrence-free survival, and prognostic factors.

    • Main Results:

    • Leiomyosarcoma (39.0%) and liposarcoma (36.6%) were the most common subtypes.
    • Overall survival rates at 1, 3, and 5 years were 92%, 69%, and 62%, respectively.
    • Liposarcomas, though larger, showed better recurrence-free survival than leiomyosarcomas; low-grade STS had better outcomes than high-grade STS.

    Conclusions:

    • The study provides insights into the clinical features and prognoses of retroperitoneal and abdominal STS in Japan.
    • Liposarcoma and leiomyosarcoma exhibit distinct clinical behaviors and locations.
    • Further large-scale nationwide studies are necessary for a comprehensive understanding of STS in Japan.