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Updated: Jun 14, 2026
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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Candidate selection for prostate cancer focal therapy.
Samir S Taneja1, Malcolm Mason
1Division of Urologic Oncology, Department of Urology, New York University Langone Medical Center, New York, New York 10016, USA. samir.taneja@nyumc.org
Journal of Endourology
|April 13, 2010
Summary
Focal therapy offers a middle ground for localized prostate cancer treatment. Careful patient selection, focusing on low-risk disease and precise mapping, is crucial for successful implementation.
Area of Science:
- Urology
- Oncology
- Medical Technology
Background:
- Focal therapy is an emerging treatment for localized prostate cancer, balancing surveillance and radical treatment.
- It presents a middle ground, potentially reducing quality-of-life impacts associated with traditional treatments.
Purpose of the Study:
- To address the primary challenge in focal therapy implementation: candidate selection.
- To define criteria for selecting patients suitable for focal therapy, particularly for curative intent.
Main Methods:
- Reviewing the role of various diagnostic tools like conventional transrectal biopsy, transperineal saturation biopsy, and prostate MRI.
- Discussing the merits and limitations of current imaging and biopsy techniques for disease mapping.
Main Results:
- Candidate selection is paramount, with initial focus on low to low-intermediate risk disease to minimize systemic failure.
- Curative focal therapy is suitable for a select group with isolated, low-risk, unifocal, or unilateral disease.
Conclusions:
- Accurate disease mapping is essential for focal therapy, requiring identification of the dominant disease site and exclusion of high-risk features.
- Despite advancements, transperineal saturation biopsy is often necessary due to limitations in current imaging modalities for precise candidate selection.
