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Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
08:03

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model

Published on: November 4, 2025

Acquired craniomeningocele in an infant with craniosynostosis: a case report

Mostafa El Khashab1, Farideh Nejat, Shahrooz Yazdani

  • 1Department of Neurosurgery, Children's Hospital Medical Center, Medical Sciences, University of Tehran, Tehran, Iran. Nejat@sina.tums.ac.ir.

Journal of Medical Case Reports
|April 13, 2010
PubMed

Insights

This case report details a rare instance of multiple suture craniosynostosis combined with an acquired craniomeningocele in an infant. This presentation highlights a unique congenital skull malformation and associated complication.

Area of Science:

  • Pediatric Neurosurgery
  • Craniofacial Anomalies
  • Congenital Malformations

Background:

  • Craniosynostosis involves abnormal skull shape, with Lückenschädel (lacunar skull) being a rare form.
  • Multiple suture craniosynostosis presents unique challenges in diagnosis and management.
  • Craniomeningocele, a protrusion of meninges and CSF through a skull defect, is uncommon.

Purpose of the Study:

  • To report a unique case of combined multiple suture craniosynostosis and acquired craniomeningocele.
  • To highlight the clinical presentation and potential management considerations for this rare condition.

Main Methods:

  • A case study of a 3-month-old Caucasian male infant.
  • Clinical presentation of multiple suture craniosynostosis and an acquired craniomeningocele.

Main Results:

  • The patient presented with multiple suture craniosynostosis.
  • An acquired craniomeningocele was identified as a lateral occipital bulging mass.
  • This represents a novel combination of these conditions.

Conclusions:

  • This is the first reported case of co-occurring multiple suture craniosynostosis and acquired craniomeningocele.
  • The findings underscore the importance of recognizing rare presentations of congenital skull abnormalities.
Abstract

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