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[Diffuse pulmonary meningotheliomatosis: an uncommon cause of the micronodular pattern]
M T Fernández Sarabia1, A Cardenal Escarcena, M Furones Díez
1Servicio de Radiodiagnóstico, Hospital Don Benito Villanueva, Badajoz, España. mtfdez70@yahoo.com
Abstract:
Pulmonary meningotheliomas are rare tumors that manifest as small nodules. They are most common in the sixth and seventh decades of life and are more common in women. Their cause is unknown and the imaging differential diagnosis should include other diseases that course with nodular patterns. Several authors have documented a statistically significant association between pulmonary meningotheliomatosis and diverse lung diseases, with adenocarcinoma of the lung being the most frequently associated disease. Very few cases of radiologically documented meningotheliomatosis have been reported. We present a case of a patient with a history of metachronous breast and rectal cancer. A micronodular pattern was observed in both lungs during CT examination to determine the extent of rectal cancer. The radiologic findings were initially interpreted as metastases and the definitive diagnosis of meningotheliomatosis was reached after lung biopsy.
Insights
Pulmonary meningotheliomas are rare lung tumors presenting as nodules. This case highlights the importance of considering meningotheliomatosis in the differential diagnosis of lung nodules, especially in patients with a history of cancer.
Area of Science:
- Oncology
- Pulmonology
- Pathology
Background:
- Pulmonary meningotheliomas are rare neoplasms presenting as small nodules.
- Their etiology remains unknown, and differential diagnoses include other nodular lung diseases.
- Pulmonary meningotheliomatosis shows a significant association with various lung diseases, notably lung adenocarcinoma.
Observation:
- A case of a patient with a history of metachronous breast and rectal cancer is presented.
- CT imaging revealed a micronodular pattern in both lungs, initially suspected as metastases.
- The definitive diagnosis of pulmonary meningotheliomatosis was established post-lung biopsy.
Findings:
- Pulmonary meningotheliomatosis can mimic metastatic disease on imaging.
- The association with prior malignancies warrants careful radiologic interpretation.
- Histopathological examination is crucial for accurate diagnosis.
Implications:
- This case underscores the need to include pulmonary meningotheliomatosis in the differential diagnosis of lung nodules.
- Radiologists and oncologists should be aware of this rare condition, particularly in patients with a history of cancer.
- Further research into the pathogenesis and diagnostic modalities for pulmonary meningotheliomatosis is warranted.
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