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Related Experiment Video

Updated: Jun 14, 2026

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
09:17

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness

Published on: May 2, 2017

Immunonutrition and critical illness: an update.

Barry A Mizock1

  • 1Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA. bmizock@earthlink.net

Nutrition (Burbank, Los Angeles County, Calif.)
|April 13, 2010
PubMed
Summary

Immunonutrition, using nutrients to support immune function, can benefit critical illness patients. However, inappropriate use poses risks, prompting a review of guidelines to clarify its safe application.

Area of Science:

  • Clinical Nutrition
  • Immunology
  • Critical Care Medicine

Background:

  • Dietary supplementation with immune-modulating nutrients shows promise in critical illness.
  • Concerns exist regarding potential harm from inappropriate immunonutrition use.
  • Clinician apprehension has limited the adoption of immunonutrition.

Purpose of the Study:

  • To discuss mechanisms of immune nutrient modulation in critical illness.
  • To review evidence-based clinical practice guidelines for adult immunonutrition.
  • To clarify controversial aspects and guide practitioners on immunonutrition use.

Main Methods:

  • Literature review of immunonutrition mechanisms.
  • Analysis of recent evidence-based clinical practice guidelines.

Related Experiment Videos

Last Updated: Jun 14, 2026

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
09:17

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness

Published on: May 2, 2017

  • Synthesis of information to provide a practitioner roadmap.

    • Main Results:

    • Immune nutrients can modulate innate and acquired immunity in critical illness.
    • Guidelines offer clarity on controversial immunonutrition issues.
    • A framework for appropriate immunonutrition application is presented.

    Conclusions:

    • Immunonutrition holds therapeutic potential in critical care when used correctly.
    • Understanding mechanisms and guidelines is crucial for safe and effective application.
    • This review aims to facilitate informed clinical decision-making regarding immunonutrition.