Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Upstream Processing01:27

Upstream Processing

Upstream processing represents a critical phase in biomanufacturing, wherein biological systems such as microorganisms, mammalian cells, or insect cells are cultivated to produce therapeutic proteins, vaccines, enzymes, or other biologically derived products. This phase encompasses all steps from the selection and genetic manipulation of the production organism to the cultivation of cells in bioreactors under tightly controlled environmental conditions.Host Selection and Genetic OptimizationThe...
Scale-Up Processes01:14

Scale-Up Processes

The scale-up of microbial fermentation processes is essential in industrial biotechnology, allowing the transition from laboratory-scale experiments to commercial-scale production while aiming to maintain product yield and quality. This process requires meticulous adjustment of equipment design, process parameters, and contamination control strategies to accommodate increasing culture volumes.At the laboratory scale, cultures are typically maintained in 1 to 10-liter glass or autoclavable...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

UVI5008: the first reversible, non-covalent Bruton's tyrosine kinase epi-inhibitor for B-cell malignancies.

Journal of hematology & oncology·2026
Same author

Energy Spectrum of Ultrahigh-Energy Cosmic Rays across Declinations -90° to +44.8° as Measured at the Pierre Auger Observatory.

Physical review letters·2026
Same author

Towards definitive functional forms for Monin-Obukhov similarity functions in stable and very stable surface layers.

Scientific reports·2025
Same author

Redefining reference intervals for baseline serum tryptase: found the solution?

European annals of allergy and clinical immunology·2025
Same author

Search for the Anomalous Events Detected by ANITA Using the Pierre Auger Observatory.

Physical review letters·2025
Same author

Inference of the Mass Composition of Cosmic Rays with Energies from 10^{18.5} to 10^{20}  eV Using the Pierre Auger Observatory and Deep Learning.

Physical review letters·2025

Related Experiment Video

Updated: Jun 14, 2026

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments
12:21

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

Published on: August 6, 2013

Decoupling MSW settlement into mechanical and biochemical processes--modelling and validation on large-scale setups.

J-P Gourc1, M J Staub, M Conte

  • 1LTHE, Grenoble University, BP 53, 38041 GRENOBLE Cedex, France.

Waste Management (New York, N.Y.)
|April 13, 2010
PubMed
Summary

Predicting landfill settlements is crucial for cover integrity. This study quantizes biodegradation

More Related Videos

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
06:24

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

Published on: December 15, 2017

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System
09:56

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System

Published on: December 23, 2022

Related Experiment Videos

Last Updated: Jun 14, 2026

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments
12:21

A Versatile Automated Platform for Micro-scale Cell Stimulation Experiments

Published on: August 6, 2013

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
06:24

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

Published on: December 15, 2017

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System
09:56

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System

Published on: December 23, 2022

Area of Science:

  • Geotechnical Engineering
  • Environmental Science
  • Biogeochemistry

Background:

  • Landfill cover integrity relies on accurate forecasting of waste settlements.
  • Secondary settlements of Municipal Solid Waste (MSW) are influenced by biodegradation.
  • Existing models often lack a comprehensive approach to biomechanical interactions in MSW.

Purpose of the Study:

  • To quantify the influence of biodegradation on secondary settlements of Municipal Solid Waste (MSW).
  • To develop and validate a biomechanical model for predicting MSW secondary settlements.
  • To assess the impact of waste pre-treatment and operational conditions on settlement components.

Main Methods:

  • Analysis of experimental data from pilot and literature studies on MSW settlements.
  • Development of a one-dimensional biomechanical model incorporating mechanical (creep) and biochemical (degradation) settlements.
  • Evaluation of biochemical settlements based on biogas production and validation using large-scale experimental data.

Main Results:

  • A novel method for predicting biochemically-induced settlements, linked to biogas production, was proposed and validated.
  • The model successfully separates and quantifies mechanical and biochemical settlement contributions.
  • Waste pre-treatment (e.g., shredding, biological pre-treatment) and operational conditions (e.g., leachate injection) significantly affect settlement components.

Conclusions:

  • Settlement in MSW landfills can be accurately predicted by combining mechanical and biochemical components.
  • Biogas production serves as a reliable indicator for estimating biochemically-induced settlements.
  • Landfill settlement monitoring is a relevant indicator for assessing the state of waste biodegradation.