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Related Concept Videos

Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Liver Regeneration01:24

Liver Regeneration

The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...
Kidney Structure01:45

Kidney Structure

The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.

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Related Experiment Video

Updated: Jun 14, 2026

Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney
08:53

Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney

Published on: August 9, 2014

Kidney regeneration.

Ariela Benigni1, Marina Morigi, Giuseppe Remuzzi

  • 1Mario Negri Institute for Pharmacological Research, Bergamo, Italy. ariela.benigni@marionegri.it

Lancet (London, England)
|April 13, 2010
PubMed
Summary
This summary is machine-generated.

Kidneys in fish can regenerate, but mammals, including humans, show limited repair. Research explores if adult mammalian kidneys possess regenerative capacity through cellular and molecular pathways.

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Last Updated: Jun 14, 2026

Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney
08:53

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Published on: August 9, 2014

Kidney Regeneration in Adult Zebrafish by Gentamicin Induced Injury
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Renal Ischaemia Reperfusion Injury: A Mouse Model of Injury and Regeneration
12:27

Renal Ischaemia Reperfusion Injury: A Mouse Model of Injury and Regeneration

Published on: June 7, 2014

Area of Science:

  • Nephrology
  • Regenerative Medicine
  • Comparative Biology

Background:

  • Neonephrogenesis, or kidney regeneration, is common in fish but rare in mammals.
  • Evidence suggests some capacity for kidney repair exists in mammals following injury.
  • Recent studies aim to understand the cellular and molecular mechanisms of renal repair.

Purpose of the Study:

  • To investigate the potential regenerative capacity of mammalian and human kidneys.
  • To clarify the cellular and molecular basis of renal repair and regeneration.
  • To address whether terminally differentiated cells, progenitor cells, or extrarenal cells contribute to kidney repair.

Main Methods:

  • Review of existing scientific literature on renal repair and regeneration.
  • Analysis of cellular and molecular pathways involved in kidney healing.
  • Examination of data from animal and human studies on kidney regenerative potential.

Main Results:

  • The review details cellular and molecular pathways implicated in renal repair.
  • Data from animal and human studies indicate a potential for kidney regeneration.
  • The study addresses the regenerative capacity of differentiated cells, progenitor cells, and extrarenal cells.

Conclusions:

  • The mammalian and human kidney may possess a greater regenerative capacity than previously thought.
  • Understanding these pathways could lead to novel therapeutic strategies for kidney disease.
  • Further research is needed to fully elucidate and harness the kidney's regenerative potential.