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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...

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Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
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Gender aspects in skin diseases.

W Chen1, M Mempel, C Traidl-Hofmann

  • 1Department of Dermatology and Allergy, Helmholtz Zentrum Munchen/TUM, ZAUM-Center for Allergy and Environment, Technische Universität München, Germany. wenchieh65.chen@gmail.com

Journal of the European Academy of Dermatology and Venereology : JEADV
|April 14, 2010
PubMed
Summary

Gender significantly impacts skin diseases, with women more prone to autoimmune and allergic conditions, while men face more infections. Understanding these sex-based differences is key for better dermatological care.

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Area of Science:

  • Dermatology
  • Medical Science
  • Gender Studies in Medicine

Background:

  • Gender disparities are well-documented across various medical fields, including anatomy, physiology, and disease epidemiology.
  • Specific to dermatology, distinct patterns emerge: males are more susceptible to infectious skin diseases, whereas females exhibit higher rates of psychosomatic issues, pigmentary disorders, hair diseases, and notably, autoimmune and allergic conditions.
  • A greater number of female-associated dermatoses have been identified compared to male-associated ones, indicating significant sex-based variations in skin health.

Purpose of the Study:

  • To explore and summarize the known gender differences in the prevalence, manifestation, and prognosis of various skin diseases.
  • To highlight the distinct dermatological conditions affecting males and females, including those in the genital area and skin malignancies.
  • To underscore the current lack of understanding regarding the underlying mechanisms of these gender differences in dermatoses.

Main Methods:

  • Review and synthesis of existing literature on gender differences in skin diseases.
  • Comparative analysis of epidemiological data and clinical observations concerning male and female dermatological conditions.
  • Identification of potential contributing factors to observed gender-based variations.

Main Results:

  • Males are more frequently affected by infectious dermatoses, while females show increased susceptibility to psychosomatic, pigmentary, and hair disorders.
  • Autoimmune and allergic skin diseases are significantly more prevalent in women.
  • Gender differences are also noted in the occurrence and outcomes of specific skin cancers and dermatoses in the genital region.

Conclusions:

  • Significant gender-based differences exist in the landscape of skin diseases, affecting susceptibility, presentation, and prognosis.
  • Factors such as skin structure, sex hormones, ethnicity, behavior, and environment likely interact to drive these disparities.
  • Further research into the mechanisms underlying these gender differences is crucial for developing targeted prevention, diagnostic, and therapeutic strategies in dermatology.