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Updated: Jun 13, 2026

Murine Prostate Micro-dissection and Surgical Castration
Published on: May 11, 2016
Prostate cancer: beta control your hormones
Massimo Loda1, William G Kaelin
1Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. massimo_loda@dfci.harvard.edu
Abstract:
Differentiation status influences the prognosis for localized prostate cancer. In this issue of Cancer Cell, Mak and coworkers describe a signaling pathway involving estrogen receptor beta (ERbeta) that governs whether prostate carcinoma cells maintain an epithelial phenotype or undergo epithelial-mesenchymal transition, suggesting that ERbeta would have prognostic or therapeutic value.
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