Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jan 10, 2026

Studying Chronic Exposure of Mice to Ultraviolet B Radiation
03:20

Studying Chronic Exposure of Mice to Ultraviolet B Radiation

Published on: August 19, 2025

1.8K

Sun-related skin diseases.

S E Prawer1

  • 1Department of Dermatology, University of Minnesota Medical School--Minneapolis.

Postgraduate Medicine
|June 1, 1991
PubMed
Summary

Excessive ultraviolet (UV) light exposure causes severe skin photoaging, leading to actinic keratoses and skin cancers like squamous cell carcinoma and basal cell carcinoma. Prevention through sun avoidance, physical barriers, and sunscreen use is crucial.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Report of a nipple nevus and an overview of accessory mammary tissue.

Cutis·1998
Same author

Accessory nipples and associated conditions.

Pediatric dermatology·1997
Same author

Drywall stilt dermatosis.

Cutis·1996
Same author

Use of a semipermeable glove during treatment of hand dermatitis.

Cutis·1996
Same author

A double-blind, vehicle-controlled paired comparison of halobetasol propionate cream on patients with plaque psoriasis.

Journal of the American Academy of Dermatology·1991
Same author

Intermittent corticosteroid maintenance treatment of psoriasis: a double-blind multicenter trial of augmented betamethasone dipropionate ointment in a pulse dose treatment regimen.

Dermatologica·1991

Area of Science:

  • Dermatology
  • Oncology
  • Preventive Medicine

Background:

  • Chronic exposure to ultraviolet (UV) radiation from natural and artificial sources induces skin photoaging.
  • Photoaging can progress to precancerous actinic keratoses and malignant skin cancers.
  • Skin cancers commonly appear on sun-exposed areas such as the head, neck, arms, and hands.

Purpose of the Study:

  • To summarize the consequences of UV-induced skin photoaging.
  • To highlight the risks and characteristics of associated skin cancers.
  • To emphasize preventive measures against UV damage.

Main Methods:

  • Review of literature on skin photoaging and UV-induced carcinogenesis.
  • Analysis of clinical presentations and metastatic potential of different skin cancer types.
  • Synthesis of recommendations for sun protection.

Main Results:

  • Severe photoaging is linked to actinic keratoses and skin cancers.
  • Squamous cell carcinomas carry a risk of metastasis, necessitating surgical excision and histology.
  • Basal cell carcinomas, while rarely metastatic, can cause significant local invasion and mortality if neglected.

Conclusions:

  • UV radiation is a primary cause of premature skin aging and skin cancer.
  • Early detection and treatment are vital, especially for squamous cell carcinoma due to metastatic potential.
  • Sun avoidance, protective clothing, and regular sunscreen application are essential preventive strategies.

More Related Videos

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

18.7K
Minimal Erythema Dose MED Testing
06:24

Minimal Erythema Dose MED Testing

Published on: May 28, 2013

42.7K

Related Experiment Videos

Last Updated: Jan 10, 2026

Studying Chronic Exposure of Mice to Ultraviolet B Radiation
03:20

Studying Chronic Exposure of Mice to Ultraviolet B Radiation

Published on: August 19, 2025

1.8K
Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

18.7K
Minimal Erythema Dose MED Testing
06:24

Minimal Erythema Dose MED Testing

Published on: May 28, 2013

42.7K