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Published on: July 20, 2022
A previously undescribed etiology for oliguria in a premature infant with a peripherally inserted central catheter
1Neonatology, Wake Medical Center, 3000 New Bern Avenue, Raleigh, NC 27610, USA. dwolfe@wakemed.org
Insights
Malpositioned peripherally inserted central catheters (PICCs) in premature infants can cause kidney damage and oliguria. Serial radiographic evaluation is crucial to ensure proper PICC placement and prevent complications.
Area of Science:
- Neonatal Medicine
- Pediatric Nephrology
- Vascular Access
Background:
- Peripherally inserted central catheters (PICCs) are widely used for long-term intravenous therapy and nutritional support in premature infants.
- While essential, PICCs are associated with potential complications that require careful monitoring.
Observation:
- A case study involving a premature infant presenting with oliguria is described.
- The suspected cause of oliguria was a malpositioned PICC tip potentially occluding renal veins or damaging kidneys via direct infusion of hypertonic parenteral nutrition.
Findings:
- Malpositioning of the PICC tip can lead to significant renal complications.
- Direct infusion of hypertonic solutions into renal vasculature can cause kidney injury.
Implications:
- Radiographic verification of PICC tip position is essential immediately after insertion.
- Serial evaluation of PICC position is critical in all infants, especially those with symptoms like oliguria or suspected sepsis.
- This highlights the importance of vigilant monitoring and imaging to prevent PICC-related morbidity in neonates.
Abstract:
Peripherally inserted central catheter use has become widespread in the management of premature infants as a means to provide long-term intravenous therapy and nutritional support until enteral feedings can be established. Peripherally inserted central catheters are not without complications. This article describes the case of a premature infant with oliguria with the suspected etiology of a malpositioned catheter tip at a location where it was either occluding/blocking the renal vein(s) or causing damage to the kidney(s) from administration of hypertonic total parenteral nutrition solution directly into the renal vein(s). Peripherally inserted central catheter position should be verified radiographically and evaluated serially in any infant, even more so in an infant with symptoms of oliguria and possible sepsis.
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