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Related Concept Videos

Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
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Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...

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Related Experiment Video

Updated: Jun 13, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Current therapies in bronchiolitis.

Frank D Petruzella1, Marc H Gorelick

  • 1Division of Emergency Medicine, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA. fpetruze@mcw.edu

Pediatric Emergency Care
|April 14, 2010
PubMed
Summary
This summary is machine-generated.

Viral bronchiolitis is a common infant hospitalization cause lacking effective treatments. This review summarizes recent trials on therapies including bronchodilators, corticosteroids, ventilation, heliox, mucolytics, and leukotriene receptor antagonists.

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A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease
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Last Updated: Jun 13, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Published on: November 4, 2010

A Minimally Invasive Method for Intratracheal Instillation of Drugs in Neonatal Rodents to Treat Lung Disease
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Published on: August 4, 2021

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Respiratory Medicine

Background:

  • Viral bronchiolitis is the leading cause of infant hospitalization.
  • Current treatment options for bronchiolitis are limited and often ineffective.
  • Significant research is ongoing to find better therapeutic strategies.

Purpose of the Study:

  • To review recent clinical trials on interventions for viral bronchiolitis.
  • To summarize the efficacy of established and novel therapies.
  • To provide an overview of current research directions in bronchiolitis treatment.

Main Methods:

  • Systematic review of recently published clinical trials.
  • Inclusion of studies evaluating bronchodilators and corticosteroids.
  • Analysis of trials on positive pressure ventilation, heliox, mucolytics, and leukotriene receptor antagonists.

Main Results:

  • Summarizes findings from recent intervention trials for infant bronchiolitis.
  • Evaluates the effectiveness of various treatment modalities.
  • Highlights emerging therapies alongside traditional approaches.

Conclusions:

  • No single consistently effective therapy for viral bronchiolitis has been established.
  • Ongoing research explores diverse interventions, including novel agents.
  • Further investigation is needed to identify optimal treatment strategies for this common infant illness.