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Related Concept Videos

Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex. This...
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
Introduction to Special Senses01:26

Introduction to Special Senses

Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive functions.
Taste Buds and Receptors01:20

Taste Buds and Receptors

Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...

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A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation
10:42

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation

Published on: August 18, 2014

Smell with new neurons.

Ti-Fei Yuan1

  • 1NCI, People's Republic of China. ytf0707@126.com

Cell and Tissue Research
|April 14, 2010
PubMed
Summary
This summary is machine-generated.

Recent discoveries reveal new neurons in adult mammalian olfactory circuits, potentially impacting smell perception and behaviors. This research opens avenues for understanding olfactory disorders and developing new treatments.

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Area of Science:

  • Neuroscience
  • Olfactory system research
  • Mammalian neurobiology

Background:

  • The olfactory system's capacity for generating new neurons in adulthood was historically debated.
  • Understanding adult neurogenesis is crucial for comprehending neural plasticity and sensory function.

Purpose of the Study:

  • To review recent findings on adult neurogenesis within mammalian olfactory circuits.
  • To highlight the potential functional implications of these new neurons on olfactory perception and behavior.
  • To suggest future research directions and therapeutic strategies for olfactory disorders.

Main Methods:

  • This work is a minireview, synthesizing existing research.
  • It focuses on studies reporting the generation of new neurons in adult olfactory pathways.
  • Analysis of findings related to the functional impact of these neurons.

Main Results:

  • Evidence confirms the generation of new neurons within adult mammalian olfactory circuits.
  • These newly generated neurons may influence olfactory perception and associated behaviors.
  • The discovery suggests a dynamic nature of the adult olfactory system.

Conclusions:

  • Adult olfactory neurogenesis represents a significant area for future investigation.
  • Understanding this process can lead to novel approaches for treating olfactory dysfunctions.
  • This research opens new possibilities for enhancing olfactory perception and related behaviors.