[Current status and perspectives in management of acute coronary syndrome]
1Osaka Medical Center for Cancer and Cardiovascular Diseases.
Insights
Acute coronary syndrome (ACS) in Japan is rising, with most deaths occurring before hospital arrival. However, advancements in emergency reperfusion and intensive treatments have significantly reduced in-hospital mortality over the past two decades.
Area of Science:
- Cardiology
- Public Health
Context:
- Acute coronary syndrome (ACS) prevalence is increasing in Japan, despite lower rates than Western countries.
- Prehospital deaths from out-of-hospital cardiac arrest constitute over half of all ACS fatalities.
- In-hospital mortality has declined over the last 20 years due to improved emergency care and treatments.
Purpose:
- To analyze trends in acute coronary syndrome (ACS) management and outcomes in Japan.
- To highlight the impact of reperfusion therapies and percutaneous coronary intervention (PCI) on ACS mortality.
Summary:
- The OACIS study indicates most ACS patients in Japan receive treatment in CCU/ER, with primary PCI being common.
- The increasing use of drug-eluting stents is associated with positive outcomes post-discharge.
- Ongoing advancements in ACS management techniques are expected to further reduce mortality rates.
Impact:
- Improved emergency reperfusion and intensive pharmacological treatments have decreased in-hospital ACS mortality.
- Widespread adoption of primary PCI and drug-eluting stents contributes to better patient outcomes.
- Continued progress in ACS management promises further reductions in mortality, enhancing patient survival and recovery.
Abstract:
Although prevalence of acute coronary syndrome (ACS) in Japan is much less than in Western countries, it steadily increases in these years. More than half of the total death from ACS are estimated to be a prehospital death due to out-of-hospital cardiac arrest. However, in-hospital mortality has been decreased during these 20 years, mainly due to the progress in reperfusion treatment at emergency care and intensive pharmacological treatment. Regional registration study(OACIS) shows that majority of the patients with ACS are transferred to CCU/ER and treated with primary PCI. Recently, use of drug eluting stent is increasing for treatment of ACS, yielding the good outcome after discharge. Further decrease in mortality is expected with the progress in ACS management technique.
More Related Videos
Related Concept Videos
01:28Acute Coronary Syndrome IV: Interprofessional Care
01:26Acute Coronary Syndrome V: Nursing Management
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
01:30Acute Coronary Syndrome I: Introduction
01:30Acute Coronary Syndrome III: Diagnostic Studies
01:26Angina IV: Management