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Fluorescence-microscopy Screening and Next-generation Sequencing: Useful Tools for the Identification of Genes Involved in Organelle Integrity
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Fluorescence-microscopy Screening and Next-generation Sequencing: Useful Tools for the Identification of Genes Involved in Organelle Integrity

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Identification of a spontaneous frame shift mutation in a nonreference Arabidopsis accession using whole genome

Roosa A E Laitinen1, Korbinian Schneeberger, Noémie S Jelly

  • 1Department of Molecular Biology, Max Planck Institute for Developmental Biology, D-72076 Tuebingen, Germany.

Plant Physiology
|April 15, 2010
PubMed
Abstract

No abstract available in PubMed .

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Point and Frameshift Mutations

Point mutations are genetic alterations involving the change of a single nucleotide base pair in DNA. Depending on how the alteration affects protein synthesis, they can lead to various consequences.Point mutations fall into the following types:Silent mutations occur when a nucleotide change does not alter the amino acid sequence due to the redundancy of the genetic code. For instance, changing ACC to ACA still encodes threonine, leaving the protein function unaffected. This occurs because...

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