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Treated arterial hypertension--which echocardiographic parameters should we monitor?
Catarina S Sousa1, Susana Gonçalves, Fausto J Pinto
1Instituto Cardiovascular de Lisboa, Lisboa, Portugal. sousa.cat@gmail.com
Insights
Uncontrolled hypertension shows early systolic and diastolic dysfunction detectable by echocardiography, even with preserved ejection fraction. Monitoring these parameters aids in early detection and management of hypertension complications.
Area of Science:
- Cardiology
- Echocardiography
- Hypertension Research
Background:
- Arterial hypertension (HTN) is a major cardiovascular risk factor.
- Early detection of cardiac dysfunction in hypertensive patients is crucial for management.
- Conventional echocardiography may not reveal subtle changes in cardiac function.
Purpose of the Study:
- To identify echocardiographic parameters that discriminate between controlled and uncontrolled arterial hypertension.
- To assess early systolic and diastolic left ventricular function in treated hypertensive patients.
Main Methods:
- Evaluated 95 patients with treated essential hypertension using conventional echocardiography and pulsed tissue Doppler imaging (TDI).
- Assessed peak systolic (Sm) and early diastolic (Em) myocardial velocities, and the ratio of mitral inflow E wave to Em (E/Em).
- Compared parameters between patients with controlled and uncontrolled HTN.
Main Results:
- Patients with uncontrolled HTN exhibited significantly reduced septal and lateral Sm (systolic function) compared to controlled HTN (p<0.005).
- Uncontrolled HTN also showed reduced septal and lateral Em (diastolic function) and increased mean E/Em (p<0.005).
- All patients had preserved ejection fraction, indicating early functional changes.
Conclusions:
- Echocardiographic parameters like Sm and Em can identify early systolic and diastolic dysfunction in uncontrolled HTN, despite preserved ejection fraction.
- Regular monitoring of these TDI-derived parameters is valuable for early detection of cardiac changes in hypertensive patients.
- Early identification of these functional changes can inform hypertension management and prevent complications.
Aims:
To identify discriminatory parameters of left ventricular systolic and diastolic function in a group of patients with treated arterial hypertension (HTN).
Methods And Results:
95 patients with treated essential HTN, recruited from a cardiology outpatient clinic, with a regular follow-up of at least one year, were evaluated with conventional echocardiography and pulsed tissue Doppler imaging (TDI). A) controlled HTN and B) uncontrolled HTN. Peak systolic (Sm) and early diastolic (Em) myocardial velocities and the ratio of mitral inflow E wave to Em (E/Em) were assessed. All patients had preserved ejection fraction. TDI study was consistent with impaired systolic and diastolic parameters in patients with uncontrolled HTN: septal Sm (cm/s) 7.8 +/- 1.8 vs. 6.8 +/- 2.2 (p = 0.004); lateral Sm (cm/s) 9.1+/- 2.8 vs. 7.7 +/- 1.7 (p = 0.001); septal Em (cm/s) 7.9 +/- 1.8 vs. 6.8 +/- 1.8 (p = 0.002); lateral Em (cm/s) 9.9 +/- 2.8 vs. 8.23 +/- 2.7 (p = 0.002); mean E/Em 8.7 +/- 2.2 vs. 10.8 +/- 3.9 (p = 0.002).
Conclusion:
In patients with uncontrolled HTN there are echocardiographic parameters that identify early changes in systolic function (reduction in septal and lateral Sm, with preserved ejection fraction) and diastolic function (with a reduction in septal and lateral Em). Regular monitoring of these parameters in hypertensive patients enables early identification of changes that may have repercussions on hypertension control.
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