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Updated: Jun 13, 2026
08:54
Measuring Blood Pressure in Mice using Volume Pressure Recording, a Tail-cuff Method
Published on: May 15, 2009
[A calibrated method for blood pressure measurement based on volume pulse wave]
Ding Youde1, Deng Qinkai, Liang Feixue
1institute of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515.
Summary
This study presents a new method for continuous, noninvasive blood pressure monitoring using pulse wave analysis. It calibrates systolic blood pressure (SBP) and diastolic blood pressure (DBP) from fingertip pulse wave propagation time.
Area of Science:
- Biomedical Engineering
- Physiology
- Medical Devices
Context:
- Continuous blood pressure monitoring is crucial for managing cardiovascular health.
- Existing methods can be invasive or provide intermittent readings.
- Accurate, noninvasive, and continuous blood pressure measurement remains a significant clinical need.
Purpose:
- To develop and validate a novel method for noninvasive, continuous blood pressure measurement.
- To establish equations for calibrating systolic blood pressure (SBP) and diastolic blood pressure (DBP) using pulse wave analysis.
- To assess the reliability and coherence of the proposed method against a standard electronic sphygmomanometer.
Summary:
- This research introduces a technique to measure blood pressure by analyzing the volume pulse wave acquired from a single fingertip.
- Systolic blood pressure (SBP) is calibrated using pulse wave propagation time, while diastolic blood pressure (DBP) is determined through regression analysis of waveform components.
- Clinical trials involving 33 participants demonstrated good coherence between the novel method and a conventional OMRON electronic sphygmomanometer.
Impact:
- This method offers a simple, reliable, and noninvasive approach for continuous blood pressure monitoring.
- It has the potential to become a valuable tool in clinical settings for improved patient management.
- The technology could advance the field of wearable health monitoring devices.
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Direct Method
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This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
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01:21Sites for measuring blood pressure
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The Brachial Artery: Primary Site for Blood Pressure Measurement
The Brachial Artery: Primary Site for Blood Pressure Measurement
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Prepare for the Procedure:
Prepare for the Procedure:
01:28Special considerations while measuring blood pressure
When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.