Related Experiment Video

Updated: Jun 13, 2026

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)
13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)

Published on: April 24, 2017

Percutaneous coronary intervention in unprotected left main coronary artery disease

Hafeez Ahmed1, Javed Majid Tai, Sajid Dhakam

  • 1Department of Medicine, The Aga Khan University Hospital, Karachi. hafeez.ahmed.@aku.edu

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|April 16, 2010
PubMed

Insights

Percutaneous coronary intervention (PCI) offers a viable treatment for unprotected left main coronary artery disease in high-risk patients. This study found PCI to be a potential alternative when surgical revascularization is not feasible.

Area of Science:

  • Cardiology
  • Interventional Cardiology

Background:

  • Unprotected left main coronary artery disease poses significant risks.
  • Surgical revascularization may not be suitable for all patients.

Purpose of the Study:

  • To evaluate the efficacy and safety of percutaneous coronary intervention (PCI) for unprotected left main coronary artery disease.
  • To assess PCI as an alternative in surgically unsuitable patients.

Main Methods:

  • Retrospective review of medical records and coronary angiography.
  • Analysis of PCI procedures in patients with >70% left main stenosis and ongoing ischemia.
  • Inclusion of patients deemed unsuitable for surgical revascularization.

Main Results:

  • Nine patients (mean age 70.1 years) were included.
  • Six patients presented with cardiogenic shock; eight had bifurcation lesions.
  • Four in-hospital deaths occurred, all in patients with cardiogenic shock; five patients survived to discharge.
  • Four patients were alive at a mean follow-up of 17 months.

Conclusions:

  • Percutaneous coronary intervention (PCI) is a potential therapeutic option for unprotected left main coronary artery disease.
  • PCI may be considered for patients with ongoing ischemia who are not candidates for surgery.
  • Outcomes were influenced by the presence of cardiogenic shock.

More Related Videos

Left Coronary Artery Ligation: A Surgical Murine Model of Myocardial Infarction05:48

Left Coronary Artery Ligation: A Surgical Murine Model of Myocardial Infarction

Published on: August 9, 2022

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

Related Concept Videos

Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...