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Updated: Jun 13, 2026

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
Published on: May 10, 2012
Study of brain anatomy with high-field MRI: recent progress
1Laboratory for Advanced MRI, LFMI, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA. jhd@helix.nih.gov
Abstract:
Recent developments in high-field magnetic resonance imaging technology have led to improved contrast and resolution and are opening up new possibilities for the study of human brain anatomy. In particular, techniques sensitized to magnetic susceptibility contrast provide particular advantages at high field that have allowed visualization of brain structures that have been difficult to detect with conventional technology. In this review, some of these developments and techniques will be discussed, and an attempt will be made to interpret magnetic susceptibility contrast based on recent studies.
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These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

