New roles for cyclin E in megakaryocytic polyploidization.

Alexia Eliades1, Nikolaos Papadantonakis, Katya Ravid

  • 1Department of Medicine and Biochemistry, Evans Center for Interdisciplinary Biomedical Research, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

Summary

Cyclin E promotes megakaryocyte (platelet precursor cell) polyploidy by driving DNA synthesis and cell cycling. This study demonstrates cyclin E

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