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Related Experiment Videos

Nonpalpable invasive breast cancer.

M C Wilhelm1, S B Edge, D D Cole

  • 1Department of Surgery, University of Virginia Health Sciences Center, Charlottesville 22908.

Annals of Surgery
|June 1, 1991
PubMed
Summary

Mammography enables early breast cancer detection, identifying invasive cancers in 18% of biopsies. Early detection significantly improves disease-free survival rates, especially in node-negative patients.

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Area of Science:

  • Oncology
  • Radiology
  • Pathology

Background:

  • Mammography is crucial for detecting nonpalpable breast abnormalities.
  • From 1980-1989, 1464 biopsies were performed for nonpalpable lesions.
  • 18% of these biopsies revealed cancerous lesions.

Purpose of the Study:

  • To analyze invasive breast cancer cases detected via mammography.
  • To evaluate the characteristics and outcomes of invasive breast cancers.
  • To emphasize the benefits of mammography in early breast cancer detection.

Main Methods:

  • Retrospective review of 86 invasive breast cancer cases.
  • Analysis of mammographic findings (mass, microcalcifications).
  • Evaluation of tumor size, histologic subtype, nodal status, and treatment modalities.

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Main Results:

  • Invasive cancers constituted 33% of all detected cancers (86 of 264).
  • Mammographic findings included masses (71%) and microcalcifications (27%).
  • Disease-free survival was 92% and overall survival was 94%, with better outcomes for node-negative patients.

Conclusions:

  • Mammography is effective in detecting invasive breast cancer.
  • Early detection through mammography is associated with high survival rates.
  • Prompt diagnosis and treatment of invasive breast cancer significantly improve patient outcomes.