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The influence of gender on the susceptibility to multiple sclerosis in sibships
A D Sadovnick1, D E Bulman, L Hashimoto
1Department of Medical Genetics, University of British Columbia, Vancouver, Canada.
Archives of Neurology
|June 1, 1991
Abstract:
A population-based study of pairs of relatives (siblings, second- and third-degree) concordant for multiple sclerosis did not show an excess of like-sexed pairs. In addition, data on human lymphocyte antigen typing for sibling pairs concordant for multiple sclerosis did not find an increase in haplotype sharing for like-sexed pairs. These data do not support the notion that sex-related factors influence multiple-sclerosis susceptibility in families.