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Related Experiment Video

Updated: Jun 13, 2026

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies

Published on: October 7, 2021

Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

Richard Hughes¹

¹MRC Centre for Neuromuscular Disease, National Hospital for Neurology and Neurosurgery, PO Box 114, Queen Square, London, WC1N 3BG, UK, rhughes11@btinternet.com

Journal of Clinical Immunology

|April 16, 2010

Summary

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare neurological disorder. Corticosteroids, IV immunoglobulin, and plasma exchange offer short-term relief, but more research is needed for effective long-term treatments.

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A Stably Established Two-Point Injection of Lysophosphatidylcholine-Induced Focal Demyelination Model in Mice

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Published on: May 11, 2022

Area of Science:

Neurology
Immunology

Background:

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a progressive or relapsing-remitting neurological disorder.
The condition affects up to 8.9 per 100,000 individuals.

Purpose of the Study:

To review the potential mechanisms of CIDP.
To evaluate the evidence for current CIDP treatments.

Main Methods:

Systematic review of existing literature.
Analysis of evidence for various therapeutic interventions.

Main Results:

Corticosteroids, intravenous immunoglobulin (IVIG), and plasma exchange are effective for short-term symptom management.
Evidence for the efficacy of other immunosuppressants is limited, despite their common use in refractory cases.

Conclusions:

Current first-line treatments provide short-term benefits.
Further high-quality clinical trials are essential to establish more effective and long-term treatment strategies for CIDP.