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The publication and database deposition of molecular interaction data
Sandra Orchard1, Bruno Aranda1, Henning Hermjakob1
1European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom.
Current Protocols in Protein Science
|April 16, 2010
Summary
Submitting molecular interaction data to public databases enhances data accessibility and visibility. This process, supported by curators and accession numbers, integrates seamlessly into manuscript preparation.
Area of Science:
- Molecular Biology
- Bioinformatics
- Data Science
Background:
- Public domain interaction databases are crucial for sharing molecular interaction data.
- Data sharing improves research reproducibility and accelerates scientific discovery.
- The International Molecular Exchange (IMEx) databases facilitate broad data dissemination.
Purpose of the Study:
- To outline protocols for submitting molecular interaction data to public databases.
- To emphasize the benefits of data deposition for researchers and the scientific community.
- To guide authors in integrating data submission into their manuscript preparation workflow.
Main Methods:
- Providing alternative protocols for data submission based on dataset size.
- Describing the process of obtaining accession numbers for pre-publication datasets.
- Detailing the use of controlled vocabulary for data standardization.
Main Results:
- Data deposition increases the quality, quantity, and visibility of molecular interaction information.
- Pre-publication submission with accession numbers enhances data accessibility in publications.
- Database curators offer assistance to ensure accurate data representation.
Conclusions:
- Integrating data submission into manuscript preparation is essential for maximizing research impact.
- Standardized data deposition practices improve data discoverability and usability.
- Public databases serve as vital resources for the molecular biology research community.
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