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Published on: January 26, 2018
[Neolignans and lignan from Piper wallichii]
Shutao Duan1, Peng Zhang, Peizhong Yu
1Department of Chemistry of Natural Drugs, School of Pharmacy, Fudan University, Shanghai 200032, China.
Summary
This study identified nine chemical compounds from the aerial parts of Piper wallichii, including one lignan and eight neolignans. Five of these compounds were newly discovered in this plant species.
Area of Science:
- Phytochemistry
- Natural Product Chemistry
Context:
- Piper wallichii is a plant species with potential medicinal properties.
- Understanding its chemical composition is crucial for further research.
Purpose:
- To isolate and identify the chemical constituents from the aerial parts of Piper wallichii.
- To elucidate the structures of the isolated compounds using spectroscopic data.
Summary:
- Nine compounds were isolated from Piper wallichii: one lignan, (-)-galbelgin, and eight neolignans (denudatin B, hancinone D, (+)-licarin A, kadsurenone, wallichinine, hancinone C, hancinone B, and (+)-burchellin).
- Compounds (-)-galbelgin, hancinone D, (+)-licarin A, hancinone B, and (+)-burchellin were reported for the first time in this plant.
Impact:
- This research expands the knowledge of Piper wallichii's chemical profile.
- The newly identified compounds may possess novel biological activities, warranting further investigation.
