Aortic Regurgitation II: Clinical Features and Diagnostic Tests
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Updated: Jun 13, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
F Guarracino1, S Pratali, R Baldassarri
1Unit of Cardiothoracic Anesthesia and Intensive Care Medicine, University Hospital of Pisa, Pisa, Italy. fabiodoc64@hotmail.com
Dilated aortic root, specifically the right sinus of Valsalva, can cause severe aortic valve regurgitation. Transesophageal echocardiography can identify this using a "Mickey Mouse" sign, guiding surgical repair.
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