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Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults

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A pilot randomized controlled trial of a clinic and home-based behavioral intervention to decrease obesity in

Lori J Stark¹, Stephanie Spear, Richard Boles

¹Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA. lori.stark@cchmc.org

Obesity (Silver Spring, Md.)

|April 17, 2010

Summary

A family-based behavioral intervention (LAUNCH) significantly reduced obesity in preschool children compared to standard care. This intensive approach improved child BMI and parent weight loss, showing lasting effects at follow-up.

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Area of Science:

Pediatrics
Public Health
Behavioral Science

Background:

Childhood obesity is a significant public health concern requiring effective interventions.
Preschool-aged children with obesity and their overweight parents are a target population for early intervention.
Current primary care approaches may lack the intensity needed for substantial obesity reduction.

Purpose of the Study:

To evaluate the efficacy of a clinic and home-based behavioral intervention (LAUNCH) for reducing obesity in preschool children.
To compare the LAUNCH intervention with enhanced standard care (Pediatrician Counseling; PC).
To assess the long-term effects of the intervention at 12-month follow-up.

Main Methods:

A randomized controlled trial involving 18 preschool children (aged 2-5 years) with BMI ≥95th percentile and an overweight parent.
Intervention group received the LAUNCH program, a family-based behavioral intervention focusing on nutrition and activity.
Control group received one-time Pediatrician Counseling (PC) with diet and activity recommendations.

Main Results:

The LAUNCH intervention resulted in significantly greater reductions in child BMI z-score, BMI percentile, and weight gain at 6 and 12 months compared to PC.
Parents in the LAUNCH group experienced significantly greater weight loss at both 6 and 12 months.
The positive effects of the LAUNCH intervention were maintained at the 12-month follow-up.

Conclusions:

An intensive, family-based behavioral intervention incorporating child behavior management strategies is more effective for reducing preschool obesity than low-intensity counseling.
The LAUNCH program demonstrates promise for sustainable obesity reduction in young children and their families.
Findings suggest that intensive interventions may be necessary for significant and lasting impact on childhood obesity in primary care settings.