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Aseptic Meningitis in Kikuchi's Disease

Hyun-Duk Yang1, Sung-Ik Lee, Il-Hong Son

  • 1Department of Neurology, Wonkwang University College of Medicine, Sanbon Hospital, Gunpo, Korea.

Journal of Clinical Neurology (Seoul, Korea)
|April 17, 2010
PubMed

Insights

Kikuchi's disease (KD) rarely affects the nervous system. This case highlights a rare Korean instance of KD with aseptic meningitis, stressing the need for awareness in meningitis diagnosis.

Area of Science:

  • Neurology
  • Rheumatology
  • Infectious Diseases

Background:

  • Kikuchi's disease (KD) is a rare, benign, lymphohistiocytic disorder.
  • Neurological involvement in KD is uncommon, with limited reports, especially from Korea.
  • Aseptic meningitis is a rare manifestation of KD.

Purpose of the Study:

  • To report a rare case of Kikuchi's disease presenting with aseptic meningitis in Korea.
  • To emphasize the importance of considering KD in the differential diagnosis of meningitis.
  • To contribute to the limited literature on neuro-Kikuchi's disease.

Main Methods:

  • Case report of a 23-year-old male patient.
  • Clinical presentation including severe headache, fever, and vomiting.
  • Cerebrospinal fluid (CSF) analysis and lymph node biopsy for histopathological diagnosis.

Main Results:

  • CSF analysis revealed elevated opening pressure, white blood cell count, and protein levels.
  • Lymph node biopsy confirmed the diagnosis of Kikuchi's disease.
  • The patient presented with concurrent aseptic meningitis.

Conclusions:

  • Kikuchi's disease can present with neurological manifestations such as aseptic meningitis.
  • Early recognition of KD is crucial for accurate diagnosis and management of meningitis.
  • This case underscores the importance of considering rare conditions in unexplained meningitis.
Keywords:
Aseptic meningitisLymphadenitisNervous system

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