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Aseptic Meningitis in Kikuchi's Disease
Hyun-Duk Yang1, Sung-Ik Lee, Il-Hong Son
1Department of Neurology, Wonkwang University College of Medicine, Sanbon Hospital, Gunpo, Korea.
Journal of Clinical Neurology (Seoul, Korea)
|April 17, 2010
Summary
Kikuchi's disease (KD) rarely affects the nervous system. This case highlights a rare Korean instance of KD with aseptic meningitis, stressing the need for awareness in meningitis diagnosis.
Area of Science:
- Neurology
- Rheumatology
- Infectious Diseases
Background:
- Kikuchi's disease (KD) is a rare, benign, lymphohistiocytic disorder.
- Neurological involvement in KD is uncommon, with limited reports, especially from Korea.
- Aseptic meningitis is a rare manifestation of KD.
Purpose of the Study:
- To report a rare case of Kikuchi's disease presenting with aseptic meningitis in Korea.
- To emphasize the importance of considering KD in the differential diagnosis of meningitis.
- To contribute to the limited literature on neuro-Kikuchi's disease.
Main Methods:
- Case report of a 23-year-old male patient.
- Clinical presentation including severe headache, fever, and vomiting.
- Cerebrospinal fluid (CSF) analysis and lymph node biopsy for histopathological diagnosis.
Main Results:
- CSF analysis revealed elevated opening pressure, white blood cell count, and protein levels.
- Lymph node biopsy confirmed the diagnosis of Kikuchi's disease.
- The patient presented with concurrent aseptic meningitis.
Conclusions:
- Kikuchi's disease can present with neurological manifestations such as aseptic meningitis.
- Early recognition of KD is crucial for accurate diagnosis and management of meningitis.
- This case underscores the importance of considering rare conditions in unexplained meningitis.
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