Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Quantum-Mechanical Model of an Atom02:45

The Quantum-Mechanical Model of an Atom

Shortly after de Broglie published his ideas that the electron in a hydrogen atom could be better thought of as being a circular standing wave instead of a particle moving in quantized circular orbits, Erwin Schrödinger extended de Broglie’s work by deriving what is now known as the Schrödinger equation. When Schrödinger applied his equation to hydrogen-like atoms, he was able to reproduce Bohr’s expression for the energy and, thus, the Rydberg formula governing hydrogen spectra. Schrödinger...
Emission Spectra02:39

Emission Spectra

When solids, liquids, or condensed gases are heated sufficiently, they radiate some of the excess energy as light. Photons produced in this manner have a range of energies, and thereby produce a continuous spectrum in which an unbroken series of wavelengths is present.
Evolution of New Traits in Microbes01:24

Evolution of New Traits in Microbes

Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...
Evolution of Microbial Genome01:08

Evolution of Microbial Genome

Microbial genome evolution is a highly dynamic process shaped by continual gene gain and loss across species and strains. This genomic flexibility allows microorganisms to adapt rapidly to environmental pressures and interactions with other organisms. Central to understanding this diversity is the distinction between the core and pan genomes.The core genome comprises the genes shared by all sampled strains of a species, representing essential functions needed for fundamental cellular processes.
Quantum Numbers02:43

Quantum Numbers

It is said that the energy of an electron in an atom is quantized; that is, it can be equal only to certain specific values and can jump from one energy level to another but not transition smoothly or stay between these levels.
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanism of Photoinduced Conformational Changes in the Photoenzyme Fatty Acid Photodecarboxylase Revealed by Light- Footprinting Ion Mobility Mass Spectrometry.

Journal of the American Chemical Society·2026
Same author

Integrated structural dynamics uncover a new B<sub>12</sub> photoreceptor activation mode.

Nature·2026
Same author

Optimising environmental factors for maximal lactate productivity in Synechocystis sp. PCC 6803 through a design of experiments approach.

Biotechnology for biofuels and bioproducts·2025
Same author

Expanding the substrate scope of a bacterial monoterpene synthase for the production of sesquiterpenoid and diterpenoid products.

The FEBS journal·2025
Same author

<i>De Novo</i> Production of Xanthohumol by a Metabolically Engineered <i>Escherichia coli</i>.

ACS synthetic biology·2025
Same author

Structural and functional insights into a novel aldehyde deformylating oxygenase with enhanced efficiency for biofuel applications.

The FEBS journal·2025

Related Experiment Video

Updated: Jun 13, 2026

Generation and Coherent Control of Pulsed Quantum Frequency Combs
06:42

Generation and Coherent Control of Pulsed Quantum Frequency Combs

Published on: June 8, 2018

Enzymology takes a quantum leap forward.

Michael J Sutcliffe1, Nigel S Scrutton

  • 1Department of Chemistry, University of Leicester, University Road, Leicester LE1 7RH, UK ( sjm@le.ac.uk ).

Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
|April 17, 2010
PubMed
Summary

Enzymes accelerate reactions by overcoming energy barriers. Recent research suggests quantum mechanics and protein dynamics, not just static barriers, are key to enzyme action, opening new avenues for enzymology.

Related Experiment Videos

Last Updated: Jun 13, 2026

Generation and Coherent Control of Pulsed Quantum Frequency Combs
06:42

Generation and Coherent Control of Pulsed Quantum Frequency Combs

Published on: June 8, 2018

Area of Science:

  • Biochemistry
  • Enzymology
  • Molecular Biology

Background:

  • Enzymes are essential biological catalysts accelerating chemical reactions.
  • Understanding enzyme catalysis has advanced significantly over the last century.
  • Genetic engineering offers tools for enzyme structure analysis and novel function design.

Purpose of the Study:

  • To explore the role of quantum mechanical phenomena and protein dynamics in enzyme action.
  • To address the limitations in understanding enzyme rate enhancement.
  • To guide future research in enzymology.

Main Methods:

  • Review of recent studies on enzyme catalysis.
  • Analysis of the role of potential-energy barriers in enzymatic reactions.
  • Investigation of quantum mechanical effects and protein motion.

Main Results:

  • Enzyme-catalyzed reactions may involve passage *through* energy barriers, not just *over* them.
  • Quantum mechanical phenomena, influenced by protein dynamics, are crucial for enzyme function.
  • Current understanding of enzyme rate enhancement is limited.

Conclusions:

  • Protein dynamics and quantum mechanics play a pivotal role in enzyme action.
  • Future enzymology research will focus on these quantum and dynamic aspects.
  • A deeper understanding of these mechanisms is needed for successful enzyme redesign.