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Updated: Jun 13, 2026

Studying the Role of Alveolar Macrophages in Breast Cancer Metastasis
07:47

Studying the Role of Alveolar Macrophages in Breast Cancer Metastasis

Published on: June 26, 2016

Metastatic angiosarcoma presenting as diffuse alveolar hemorrhage.

Sp Rai1, Ms Barthwal, P Bhattacharya

  • 1Department of Respiratory Medicine, Military Hospital (Cardio-Thoracic Centre), Pune., India.

Lung India : Official Organ of Indian Chest Society
|April 17, 2010
PubMed
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We present a rare case of angiosarcoma, a vascular cancer, that spread to the lungs. This cancer initially presented as diffuse alveolar hemorrhage, a serious bleeding condition in the lungs.

Area of Science:

  • Oncology
  • Pulmonary Medicine
  • Pathology

Background:

  • Angiosarcoma is a rare malignant neoplasm arising from vascular or lymphatic endothelial cells.
  • Diffuse alveolar hemorrhage (DAH) is an uncommon but serious clinical presentation.
  • Malignant neoplasms, particularly angiosarcoma, can manifest with DAH.

Purpose of the Study:

  • To report a unique case of pulmonary angiosarcoma metastasis.
  • To highlight DAH as an initial presenting manifestation of metastatic angiosarcoma.
  • To contribute to the understanding of rare angiosarcoma presentations.

Main Methods:

  • Case report detailing clinical presentation, diagnostic workup, and histopathological findings.
  • Review of relevant literature on angiosarcoma and diffuse alveolar hemorrhage.
Keywords:
AngiosarcomaDiffuse alveolar hemorrhageMetastatic

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Last Updated: Jun 13, 2026

Studying the Role of Alveolar Macrophages in Breast Cancer Metastasis
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Main Results:

  • The patient presented with diffuse alveolar hemorrhage as the first sign of disease.
  • Histopathological examination confirmed pulmonary metastasis of angiosarcoma.
  • The case underscores the potential for angiosarcoma to present atypically.

Conclusions:

  • Diffuse alveolar hemorrhage can be the initial manifestation of metastatic angiosarcoma.
  • Early recognition and diagnosis are crucial for managing this rare condition.
  • This case expands the spectrum of known presentations for angiosarcoma.