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A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
[Analysis of the diabetes mellitus screening program in the Federal District, Mexico]
Maria Guadalupe Alvear-Galindo1, Asa Cristina Laurell
1Facultad de Medicina, Universidad Nacional Autónoma de México, México, DF, México. alvear@servidor.unam.mx
Abstract:
From the public health perspective, programs to detect type 2 diabetes mellitus are a prime resource for surveillance of the disease. As a screening strategy, the Mexican Ministry of Health implemented the Diabetes Mellitus Action Program (PADM-2), based on two sequential tests: the Risk Factor Questionnaire and capillary blood glucose test. This study explored the Program's capacity as a screening strategy. The study was carried out in the year 2005, with a sample of 1,562 that attended six primary care units under the Health Secretariat of the Federal District. Fasting serum glucose was defined as the gold standard. When assessing the two tests sequentially, sensitivity was 98%, specificity 58.7%, and positive predictive value 16.6%. The positive predictive values indicates that a high proportion of the expenditure still goes to detecting false-positives, thus requiring reconsideration of the Program's criteria to obtain a greater economic and social benefit.
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